Antibody Inverse Folding

IgDesign™: Antibody inverse folding with in vitro validation

IgDesign™ is the first experimentally validated antibody inverse folding model. It can design antibody binders to multiple therapeutic antigens with high success rates and, in some cases, improved affinities over clinically validated reference antibodies. Antibody inverse folding has applications to both de novo antibody design and lead optimization, making IgDesign™ a valuable tool for drug development and enabling therapeutic design.